Phenylephrine reddit.

Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients.Push-dose vasopressors, or push-dose pressors, refers to administration of intermittent, small doses of vasopressors to optimize a patient’s hemodynamic status [2, 3]. Commonly used push-dose vasopressors include epinephrine and phenylephrine [2, 3]. Push-dose administration is a long standing practice amongst anesthesiologists to …2 great_site_not • 5 yr. ago You need different friends. 200mg of phenylephrine is extremely dangerous, and anyone who'd hand it to you and tell you it's fine is dangerously negligent (assuming it wasn't malicious). Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating alpha-1 adrenergic receptors in the ...Will Phenylephrine get me high? I have a bunch of Phenylephrine and I was wondering if I took this I would feel anything I have abt 34 pills and I just wanted to know if this stuff would get me high or not? This thread is archived New comments cannot be posted and votes cannot be cast 3 13 comments Best Top New Controversial Q&A

It wasn’t until 1976 that the F.D.A. began reviews of over-the-counter cold medicines, like phenylephrine, as a class of drugs. But by the early 1990s, the decongestant still hadn’t received a ...Phenylephrine is a vasoconstrictor - which reduces sinus congestion by shrinking capillaries and veins. Also, from Wikipedia: Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo for allergy relief.TIL that Phenylephrine, the nasal decongestant that replaced pseudoephedrine in OTC cold medicine, was shown to be ineffective vs placebo at up to 4X the recommended …

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Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients. I just discovered a wicked legal phenylalanine high. Just hold any drink with phenylalanine added under the tongue for about 15-30 seconds and you'll be halfway to mars faster …Phenylephrine is found in common cold medicines but it doesn't actually work when taken orally, advisers said. But before you toss your meds, here's some context. Jessica is a writer on the ...The Consumer Healthcare Products Association, a group that represents over-the-counter drug manufacturers, said it is against removing oral phenylephrine from the market, adding that it is the ...Phenylephrine is an alpha-agonist - that is, it works at "alpha receptors" in our body. The main effects of these receptors is to cause things to squeeze, like blood vessels, for example. That's how they work on congestion - squeezed vessels = less leaky. Phenylephrine mainly works on the alpha-1 receptors, and that's what their job is - …

3 sept. 2012 ... ... phenylephrine (found in Neo- Synephrine and its generics), which lasts up to four hours. Get the full experience.Choose your plan. While ...

View community ranking In the Top 1% of largest communities on Reddit. Japanese Throats [serious] ... Acetaminophen 325 mg (Pain reliever/fever reducer) Dextromethorphan HBr 10 mg (Cough suppressant) Phenylephrine HCl 5 mg (Nasal decongestant) Paburon Active Ingredients (per 1.3g pack dose) Ibuprofen 150 mg, Bromohexine hydrochloride 4 mg ...

Could cause high blood pressure during the duration of the experience. I imagine it could come with a significant amount of nausea as well. Don't be so stupid with drugs again though! It could cost you your life or your future! Drugs can be very useful tools, but if you don't respect them, learn everything you can about what you're putting in ...DEAR MAYO CLINIC: I have used decongestants over the years when I'm ill, but my doctor recently said that I should be cautious because nonprescription decongestants can have significant side effects. Is this true? ANSWER: While many people rely on nasal decongestants to help ease nasal symptoms of a cold or flu, these medications can sometimes cause […]Aug 17, 2023 · The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, whereas there is some evidence that oral PDE is effective. The main reasons for a lack of effectiveness of PE include: Although both PE and PDE are well absorbed from the gut, PE is extensively metabolized ... Ticoll B and Shugar G. have reported that fully related these effects to a 41-year old patient suffering from paranoid psychosis as the result of use of nasal oxymetazoline spray [12]. Snow SS. has reported the addition to phenylephrine in a 26-year old patient which actually resulted in toxic psychosis [13].13 sept. 2023 ... 11-12 to decide if the drug phenylephrine should continue to be sold as a treatment for nasal decongestion. ... Reddit; Copy Link to Blog Post.DEAR MAYO CLINIC: I have used decongestants over the years when I'm ill, but my doctor recently said that I should be cautious because nonprescription decongestants can have significant side effects. Is this true? ANSWER: While many people rely on nasal decongestants to help ease nasal symptoms of a cold or flu, these medications can sometimes cause […]

An ingredient in many over-the-counter (OTC) decongestants, phenylephrine is present in more than 200 different OTC products, including Sudafed …The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills.Evidence of phenylephrine's effectiveness comes from a review that combined and analyzed the results of seven individual studies. It found the drug had a small but real effect on nasal airway ...Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output. Reply.2 ks99 • 10 yr. ago It is not a mystery chemical, it is used as a decongestant that has largely replaced pseudoephedrine in OTC medications (pseudo is behind the counter where I'm from). I would not take anything that didn't have only DXM in though as well.View community ranking In the Top 5% of largest communities on Reddit. Why SBP is increased in Phenylephrine and Norepinephrine? ... SBP depends on cardiac output So according to this concept DBP should rise but not SBP , infact SBP should decrease as phenylephrine causes reflex bradycardia and this bradycardia decreases cardiac output …

4 comments [deleted] • 5 yr. ago Phenylephrine works as a vasoconstrictor, which raises BP and heart rate. Probably why its associated with an increased risk of …Location. belly of the beast, MA. Feb 14, 2011. #15. based on experience, i wouldn't take more than 20-60mg of dxm on wellbutrin. that will be enough to give an effect, any more gets to be nasty. also, this combo can cause serotonin syndrome, i've gotten it from combining even as little as 350mg of dxm with wellbutrin, and i weigh 240lbs/.

Push-dose vasopressors, or push-dose pressors, refers to administration of intermittent, small doses of vasopressors to optimize a patient’s hemodynamic status [2, 3]. Commonly used push-dose vasopressors include epinephrine and phenylephrine [2, 3]. Push-dose administration is a long standing practice amongst anesthesiologists to …A key ingredient in many over-the-counter cold and allergy medications called phenylephrine doesn’t work to get rid of nasal congestion, a Food and Drug Administration advisory panel concluded ...Yes i am aware of the side effects. No i do not really mind them they are better then falling asleep at my desk. (And i’ve read you can get a bit of a high out of em too. 😁) It's a terrible "decongestant" and causes migraines for many people. Not much of a stim. Here at Lifehacker, we are endlessly inundated with tips for how to live a more optimized life—but not all tips are created equal. The best ones are the ones that stick; here are the tips with the greatest longevity, according to Reddit. He...View community ranking In the Top 1% of largest communities on Reddit. Japanese Throats [serious] ... Acetaminophen 325 mg (Pain reliever/fever reducer) Dextromethorphan HBr 10 mg (Cough suppressant) Phenylephrine HCl 5 mg (Nasal decongestant) Paburon Active Ingredients (per 1.3g pack dose) Ibuprofen 150 mg, Bromohexine hydrochloride 4 mg ...Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating …

Phenylephrine is a direct-acting sympathomimetic amine that functions as an alpha-1 adrenergic agonist. Its chemical structure is related to epinephrine and ephedrine and possesses potent vasoconstriction properties when given intravenously or applied directly to mucosal membranes.

The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills.

Other pharmacists have expressed concerns over phenylephrine's effectiveness as a nasal decongestant,[1] and other clinicians have indicated concern for regulatory actions that reduced the availability of pseudoephedrine.[12][13] A subsequent meta-analysis by the same researchers concluded that there is insufficient evidence for its ...Last updated on Aug 17, 2023. Official answer by Drugs.com The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, whereas there is some evidence that oral PDE is effective. The main reasons for a lack of effectiveness of PE include:According to Sudafed.com, Sudafed uses pseudoephedrine as a nasal decongestant, while Sudafed PE uses phenylephrine or PE. Sudafed.com notes that the original Sudafed formula and Sudafed PE provide relief from sinus congestion and pressure ...Phenylephrine, the nasal decongestant in many cold medicines, found ineffective by FDA panel. The leading decongestant used by millions of Americans looking for relief from a stuffy nose is likely ...Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating alpha-1 adrenergic receptors in the ...The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills. 7 Year addiction to oxymetazoline based nasal sprays finally over. Not sure if this is the right place to post this but yeah. Man, I used to smoke like a chimney and drink like a fish but nasal spray was the hardest thing to quit. Started using them in Jan 2010. Jan 4th actually. A warning about stimulants and cold medicine. In a nutshell, I was on 10 of Prozac titrating up to 20 slowly, and had just increased my dose of Vyvanse again when my asthma flaired up. I had to take my Albuterol inhaler and Robitussin with dextromethorphan and guaifenesin. I had a nightmare response that caused a crazy panic episode that lasted ... A website’s welcome message should describe what the website offers its visitors. For example, “Reddit’s stories are created by its users.” The welcome message can be either a statement of purpose or brief extracts from the most-important p...Feb 25, 2020 · Phenylephrine is an over-the-counter nasal decongestant available in 5 mg and 10 mg tablets, as well as an oral solution. It is also available in an injectable form which is only used in an inpatient setting by medical professionals for low blood pressure. Phenylephrine can be purchased without restriction or logging of the purchaser’s ... Dec 20, 2022 · Key takeaways: Sudafed (pseudoephedrine) and Sudafed PE (phenylephrine) are decongestant medications that treat nasal and sinus congestion. Sudafed is generally more effective at relieving nasal and sinus congestion than Sudafed PE, but it has more risks. Sudafed has some purchase restrictions, so it’s only available behind the pharmacy ...

But be that as it may: the fact remains that its alleged replacement, phenylephrine, is of no real use and does not deserve its FDA listing. There's no reason …According to Wikipedia: "Methcathinone production utilizes the oxidation of pseudoephedrine or ephedrine, the former being preferred because of much higher yields achieved. Oxidation of pseudoephedrine to methcathinone requires little chemistry experience, making it (relatively) easy to synthesize. [5] [unreliable source?]Reddit; Wechat; Abstract. Aim. ... followed by 13–16 μg norepinephrine and 81–120 mg phenylephrine; 121–150 μg phenylephrine had the highest probability (62%) caused reactive hypertension, followed by 11–30 mg ephedrine; phenylephrine was most likely to cause bradycardia in a dose-dependent manner; 81–120 μg phenylephrine had …View community ranking In the Top 50% of largest communities on Reddit. ... I just traded my oxymetazoline dependence for phenylephrine. Both are just as bad in terms of rebound and dependence. Also, interestingly enough, afrin no longer worked for me while I was taking phenylephrine. Like it wouldn’t clear out my nose as it used to. ReplyInstagram:https://instagram. free rbt practice exam 20234221 way out west drivedorchester county mugshotsdemarini voodoo 2 piece 17 sept. 2015 ... Results were the same for four different drug doses of phenylephrine. For most patients with allergic rhinitis, nasal congestion is the most ... publix super market at mauldin squarenewsmax wake up america female host Phenylephrine is the stuff they used to replace pseudoephedrine after people start making meth with it. It's not as good, but if it gets the job done, it gets the job done. It's probably the Phenylephrine that makes it work better than just a pure antihistamine. You can probably get the same effect with any antihistamine + decongestant.The best non-prescription, safe, legal ADHD "mitigatior" that I have found is xenon. It greatly helps with meditation, is anti-anxiety, and apparently helps with exercise as well. It will not "cure" ADHD -- that is a very complex issue. It is more expensive than most nootropic pills -- but google around and find something you can affore. lounge.learningcaregroup oracle Guaifenesin is an expectorant sold under the brand name Mucinex, Bidex, Organidin, Robafen, and others. Guaifenesin reduces the viscosity of mucus so it can be easily coughed up. Guaifenesin is found in many multi-symptom cold & cough medicines, including: Coricidin HBP Day & Night Multi-Symptom Cold. Robitussin DM.The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, …